We are pleased to welcome Dr Basil Greber, whose research focuses on elucidating the molecular mechanisms underlying DNA repair and transcription using advanced structural biology techniques. Dr Greber鈥檚 work leverages cutting-edge cryo-electron microscopy (cryo-EM) to investigate large macromolecular assemblies and their roles in maintaining genome integrity.
In this seminar, Dr Greber will present insights into the structure and function of key protein complexes involved in nucleotide excision repair (NER), a critical pathway responsible for detecting and repairing DNA damage. Dysfunction in this pathway is closely linked to human disease, including cancer, emphasising the importance of understanding these processes at a molecular level.