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• Journal article
  Bottle A, Middleton S, Kalkman CJ, Livingston EH, Aylin Pet al., 2013,
  , HEALTH SERVICES RESEARCH, Vol: 48, Pages: 2081-2100, ISSN: 0017-9124
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  • Citations: 60
• Journal article
  Nouraei SAR, Middleton SE, Hudovsky A, Darzi A, Stewart S, Kaddour H, Alam P, Jallali N, Birchall MA, Ghufoor K, Aylin P, Clarke PM, Bottle Aet al., 2013,
  , CLINICAL OTOLARYNGOLOGY, Vol: 38, Pages: 502-511, ISSN: 1749-4478
  • Cite
  • Citations: 38
• Journal article
  Alexandrescu R, Bottle A, Jarman B, Aylin Pet al., 2013,
  , BMC HEALTH SERVICES RESEARCH, Vol: 13, ISSN: 1472-6963
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  • Citations: 18
• Journal article
  Burns EM, Bottle A, Almoudaris AM, Mamidanna R, Aylin P, Darzi A, Nicholls RJ, Faiz ODet al., 2013,
  , BRITISH JOURNAL OF SURGERY, Vol: 100, Pages: 1531-U1538, ISSN: 0007-1323
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  • Citations: 30
• Journal article
  Bottle A, Sanders RD, Mozid A, Aylin Pet al., 2013,
  , INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 168, Pages: 338-343, ISSN: 0167-5273
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  • Citations: 9
• Journal article
  Bottle A, Mozid A, Grocott HP, Walters MR, Lees KR, Aylin P, Sanders RDet al., 2013,
  , BRITISH JOURNAL OF ANAESTHESIA, Vol: 111, Pages: 417-423, ISSN: 0007-0912
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  • Citations: 10
• Journal article
  Mamidanna R, Almoudaris AM, Bottle A, Aylin P, Faiz O, Hanna GBet al., 2013,
  , SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 27, Pages: 3348-3358, ISSN: 0930-2794
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  • Citations: 17
• Journal article
  Ruiz M, Bottle A, Aylin P, 2013,
  , JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, Vol: 106, Pages: 362-369, ISSN: 0141-0768
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  • Citations: 24
• Journal article
  Symons NRA, Moorthy K, Almoudaris AM, Bottle A, Aylin P, Vincent CA, Faiz ODet al., 2013,
  , BRITISH JOURNAL OF SURGERY, Vol: 100, Pages: 1318-1325, ISSN: 0007-1323
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  • Citations: 154
• Journal article
  Tsang C, Bottle A, Majeed A, Aylin Pet al., 2013,
  , BMC Health Services Research, Vol: 13, Pages: 1-9, ISSN: 1472-6963

  BackgroundPatients diagnosed with cancer by the emergency route often have more advanced diseases and poorer outcomes. Rates of cancer diagnosed through unplanned admissions vary within and between countries, suggesting potential inconsistencies in the quality of care. To reduce diagnoses by this route and improve patient outcomes, high risk patient groups must be identified. This cross-sectional observational study determined the incidence of first-ever diagnoses of cancer by emergency (unplanned) admission and identified patient-level risk factors for these diagnoses in England.MethodsData for 74,763 randomly selected patients at 457 general practices between 1999 and 2008 were obtained from the General Practice Research Database (GPRD), including integrated Hospital Episode Statistics (HES) data and Office for National Statistics (ONS) mortality data. The proportion of first-ever diagnoses by emergency admission out of all recorded first cancer diagnoses by any route was analysed by patient characteristics.ResultsDiagnosis by emergency admission was recorded in 13.9% of patients diagnosed with cancer for the first time (n = 817/5870). The incidence of first cases by the emergency route was 2.51 patients per 10,000 person years. In adjusted regression analyses, patients of older age (p < 0.0001), living in the most deprived areas (RR 1.93, 95% CI 1.51 to 2.47; p < 0.0001) or who had a total Charlson score of 1 compared to 0 (RR 1.34, 95% CI 1.06 to 1.69; p = 0.014) were most at risk of diagnosis by emergency admission. Patients with more prior (all-cause) emergency admissions were less at risk of subsequent diagnosis by the emergency route (RR 0.31 per prior emergency admission, 95% CI 0.20 to 0.46; p < 0.0001).ConclusionsA much lower incidence of first-ever cancer diagnoses by emergency admission was found compared with previous studies. Identified high risk groups may benefit from int

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