Project Title: Mechanistic investigation of Temporal Interference brain stimulation and its translational application
Supervisor: Dr Nir Grossman
Location: Level 5, Burlington Danes Building, Hammersmith Campus, Du Cane Road, W12 0NN
About Me
Patrycja completed her PhD at the Centre for Doctoral Training in Neurotechnology, where she focused on developing and validating a non-invasive deep brain stimulation technique called Temporal Interference. Prior to joining 天美传媒, Patrycja earned her MEng degree in biomedical engineering at University College London (UCL). During that time, she developed a keen interest in the interaction between biological systems and technology, leading her to work in robotics and neuroscience laboratories on developing body- and brain-machine interfaces. Having experienced the importance of both basic and clinical research, Patrycja decided to pursue a PhD project at the intersection of these worlds. She is now a postdoc at Stanford University in the USA.
Qualifications
- 2019-2024 PhD in Clinical Medicine Research, 天美传媒
- 2018-2019 MRes in Neurotechnology and PhD in Medicine, 天美传媒
- 2014-2018 MEng Biomedical Engineering, University College London (First Class Hons)
Patents
Dzialecka P*, Grossman N*. . Pulsed Temporal Interference technology
Research Interests
Physical means of brain stimulation, such as with the use of implanted electrodes for deep brain stimulation (DBS), offer a non-pharmacological approach to probe and treat dysfunctional neural networks by directly controlling circuit activity. DBS is widely used to treat patients with severe movement and affective disorders. However, the risks associated with inserting electrodes into the brain limit the therapeutic impact of DBS and make it challenging to explore new brain targets.
A novel stimulation technique called Temporal Interference (TI), unlike most other techniques, shows the potential to reach deep brain regions without activating the overlying structures. The overall aim of my PhD project was to develop stimulation principles to pave the way for new experimental frontiers and therapies with reduced risk for patients. My project focused primarily on characterising the large-scale, spatiotemporal neuronal responses to TI and developing stimulation paradigms aimed at alleviating the progression of Alzheimer’s Disease.
Selected publications
Luff CE, Dzialecka P, Acerbo A, Williamson A, Grossman N, Pulse-Width Modulated Temporal Interference (PWM-TI) Brain Stimulation. , 2024
Wessel MJ*, Beanato E*, (…), Dzialecka P, (…), Hummel FC. Noninvasive theta burst stimulation of the human striatum enhances striatal activity and motor skill learning. , 2023
Acerbo E, Jegou A, Luff C, Dzialecka P, (…), Williamson A. Focal non-invasive deep-brain stimulation with temporal interference for the suppression of epileptic biomarkers. , 2022
De Santis D, Dzialecka P, Mussa-Ivaldi FA. Unsupervised Coadaptation of an Assistive Interface to Facilitate Sensorimotor Learning of Redundant Control. , 2018
Contact Details
LinkedIn:
